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Nanopore profiling: a scalable approach to protein identification

22/05/2023 - Journal Club

Nanopore profiling: a scalable approach to protein identification

by Chiara Sopegno and Arthur Grimaud

Proteomics research relies heavily on mass spectrometry, which has emerged as the most prominent and widely utilized approach for the identification of proteins. However, progress is being made in other analytical methods for peptides and proteins. In this month PROTrEIN ITN’s Journal Club, we are taking a glance at the characterization of proteins with nanopores […]

Papers and patents are becoming less disruptive over time

03/04/2023 - Journal Club

Papers and patents are becoming less disruptive over time

by Marc Pauper and Ayesha Feroz

The fields of science and technology have been the engines of progress for many years, driving innovation and shaping the world we live in. Contributing to this scientific knowledge and progress is one of the main aspirations most of us researchers have. However, there is a growing number of studies suggesting that scientific progress is […]

Changing the proteomics shell towards the DIA-world

27/03/2023 - Journal Club

Changing the proteomics shell towards the DIA-world

by Pinar Altiner and Shamil Urazbakhtin

Data-independent acquisition (DIA) proteomics increasingly becomes the method of choice for researchers since it provides better reproducibility, identification rates, and accuracy compared to data-dependent acquisition (DDA). More and more tools are developed for DIA analysis and even established proteomics data processing software now can analyze DIA data. However, analysis of multiplexed spectra, characteristic of DIA, […]

Are you a morning person? – Chronotypes, Circadian Rhythms, and Questionnaires

22/02/2023 - Journal Club

Are you a morning person? – Chronotypes, Circadian Rhythms, and Questionnaires

by Prajwal DSouza and Carlo De Nart

Life as we know it has been shaped by the constraints of the environment. The aerodynamic shape of leaves to prevent the tree from toppling at high winds, or gravity that affects heights of organisms (extraterrestrial humanoids on the fictional pandora in Avatar), or the color of a polar bear. The environment is a critical […]

Casanovo, a transformer model to identify De novo mass spectrometry peptide sequencing

10/02/2023 - Journal Club

Casanovo, a transformer model to identify De novo mass spectrometry peptide sequencing

by Zahra Elhamraoui and Mostafa Kalhor

In the last Journal club, we present a paper by Yilmaz et al. called «De novo mass spectrometry peptide sequencing with a transformer model» [1] introducing a deep learning model for de novo peptide sequencing. What? You do not know exactly what is de novo peptide sequencing? Let me explain it. Imagine that you do […]

Recalling memories of our first in-person project meeting and SciComm training school in the beautiful city of colours ‘Barcelona’

12/12/2022 - News

Recalling memories of our first in-person project meeting and SciComm training school in the beautiful city of colours ‘Barcelona’

by Ayesha Feroz and Alireza Nameni

Consortium meeting: After we ESRs had participated in the 13th International MaxQuant Summer School on Computational Mass Spectrometry-based Proteomics, the opening dinner of the consortium meeting was the first time that all PROTrEIN members, incl. supervisors, actually met in person. The venue was amazingly beautiful and close to the sea. Where we all enjoyed a […]

Wikipedia Hackathon Experience

28/11/2022 - News

Wikipedia Hackathon Experience

by Prajwal D'Souza and Zahra Elhamraoui

Most of us do research because we enjoy finding answers, solving problems and even helping people. But there is also a deep seated human tendency to leave a mark. Contribute to a bigger picture, graffiti on your neighbor’s wall, advance a field. This is probably why we write research papers. (Apart from begging for funding […]

Organising a large event as a first year PhD student – behind the scenes of the MaxQuant Summer School 2022

21/11/2022 - News

Organising a large event as a first year PhD student – behind the scenes of the MaxQuant Summer School 2022

by Carlo De Nart

Starting with the premise that I have never organised such a big event in the past, getting actively involved in the organisation of the MaxQuant summer school (MQSS) has been a great opportunity to learn skills that are usually not directly related to pure research in science. The whole process of organising the summer school […]

“Cross-Linking Mass Spectrometry: A sneak peak into its world!! ”

26/06/2022 - Journal Club

“Cross-Linking Mass Spectrometry: A sneak peak into its world!! ”

by Louise Buur and Ayesha Feroz

It has been a while since our official PROTrEIN launch. We’ve had monthly ESR meetings during this time, where the majority of us have been able to discuss more details about our projects and present them to the group. Several ESRs are working on developing new tools and data analysis pipelines to improve cross linking […]

Proteins form functional networks, and so do people – the first PROTrEIN summer school

16/12/2021 - News

Proteins form functional networks, and so do people – the first PROTrEIN summer school

by Marc Pauper and Mostafa Kalhor

The first PROTrEIN annual meeting and summer school took place between the 10th and 23rd of September 2021. Here our ESRs Marc and Mostafa share their thoughts and memories about it.

How can proteomics data become more reproducible?

14/10/2021 - Journal Club

How can proteomics data become more reproducible?

by Louise and Shamil

In this Journal Club, our ESRs Louise and Shamil present the article «Strategies to enable large-scale proteomics for reproducible research» by R. Poulos et al. from July 2020