Centre for Genomic Regulation (CRG)
Eduard Sabidó is the head of the Proteomics Unit of the Centre for Genomics Regulation and the University Pompeu Fabra. Eduard holds degrees in Biochemistry, Biology, and Computer Sciences, and a doctorate in Biology from the University of Barcelona. Eduard was trained in mass spectrometry at the Institute for Research in Biomedicine, and the Swiss Federal Institute of Technology in Zurich under the supervision of Prof. Ernest Giralt, and Prof. Ruedi Aebersold. His research interests focus on the development of innovative mass spectrometry methods and computational tools for the quantification of proteins in biological samples.
Proteomics technologies connect the biological complexity with the molecular pathological mechanisms, and they are used in many translational research projects for both the diagnosis, and the understanding of disease mechanisms. The CRG/UPF Proteomics Unit focuses its technological research activities on the development of mass spectrometric methods for targeted protein quantitation, the characterization of protein interactions, and the identification of protein post-translational modifications with high sensitivity, reproducibility, accuracy and precision. The Unit tackles several aspects to overcome the current analytical limitations to enable rapid, high-quality proteome quantification in patient biopsies, tissues, and cell cultures. The main research goals of the Unit are to define what peptides are the best protein surrogates for protein quantification in whole-proteome analyses, to extend the precision and accuracy of single-biomarker methods to whole-proteome quantification analyses, and to develop highly sensitive acquisition methods compatible with fast proteome analyses for high sample throughput. The CRG/UPF Protoemics Unit is part of the Spanish National Infrastructure of Omics Technologies (ICTS OmicsTech) and the European consortium EPIC-XS (2019-2022).